Learn about the potential side effects of iron protein succinylate. Includes common and rare side effects information for consumers and healthcare professionals. Name: Iron protein succinylate; Accession Number: DB; Type: Small Molecule; Groups: Approved, Investigational; Description: Not. View pharmacology details for the Iron protein succinylate generic medicine.
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With this medication, 63 patients The authors review the relevant literature and report a case of Toxic Epidermal Necrolysis Syndrome where two medications, iron protein succinylate and dabigatran, not previously associated with the disorder might have acted as precipitants to it.
Iron protein succinylate Side Effects
The most significant adverse effect of repeated oral administration of iron-containing antianaemic preparations is the gastroduodenal toxicity, attributable to a direct toxic effect of iron on the glandular epithelium. Toggle navigation Medicine India. The aim of this study was to evaluate the efficacy and tolerability of iron protein succinylate sucfinylate the treatment of iron-deficiency anemia in pregnancy.
A systematic review was conducted to analyze the tolerability of several oral iron supplements based prptein data obtained in available publications and to report the incidence of adverse effects AEs for each supplement both overall and gastrointestinal.
Five hundred and forty-nine patients received ITF ; patients were treated with ferrous sulphate. Page prohein of 1. Histological damage to the gastroduodenal mucosa was evaluated using light and electron microscopy.
Curr Med Res Opin Apr 6;29 4: Clin Drug Investig ;25 The ITF absorption process, like that of ferritin, proceeds along the physiological pathways without bypassing the transfer system of the intestinal mucosal cells since no succinylqte increase of serum metal is observed when giving high doses of ITF to the rat pretreated with a saturating dose of ferrous sulphate. The criteria for the diagnosis of anemia were Hb Read More.
Serum iron curves were determined in two groups of iron deficient patients after oral administration of iron protein succinylate or ferritin. J Pharm Pharmacol Jun;43 6: Controlled, double-blind, multicenter clinical trial of iron protein succinylate in the treatment of iron deficiency in children.
Iron protein succinylate is an iron-protein complex, in which iron is present in ferric form. A product containing a high amount of iron and maintaining all the necessary characteristics of stability and solubility for a drug can be prepared by succinylating the proteins, in the specific case the milk proteins, before the reaction with the iron salt.
Iron protein succinylate
Both treatments lasted 60 days. Assay samples were treated with 0. ITF are presented.
proteun Iron protein succynilate in the treatment of iron deficiency: Akush Ginekol Sofiia ;41 Suppl 1: An Med Prohein Dec;19 Physical Medicine and Rehabilitation The overall clinical rating was significantly in favor of ITFwith Iron protein succinylate in the treatment of iron deficiency: For these derivatives a particular advantage can be achieved, the iron succinyl protein precipitates at the pH of the stomach further keeping the iron bonded and it re-solubilizes at pH higher than 7, the intestine pH level.
Arzneimittelforschung Nov;45 Succinglate Xing Xiao-Mei Tong. ITF, a soluble iron succinyl-protein complex, orally administered to the rat elevates the concentration of iron in the serum to a greater extent than ferritin.
A comparative study on the gastroduodenal tolerance of different antianaemic preparations.
Some of the brands for iron protein succinylate might be better known than iron protein succinylate itself. Flavio Lazzari Maria Carrara.
Iron protein succinylate – DrugBank
Acute allergic reaction to an iron succinylafe in a milk-allergic patient. Evaluation of the siderohaemic curve after loading administration of iron–protein–succinylate to gastrectomized subjects: Iron protein succinylate is a new iron preparation for oral administration.
Electrophoresis indicates that the iron succinyl protein is homogeneous and gel filtration shows an apparent high molecular weight that contributes to the stability of the complexed iron. Sign In Join Now. One oral vial of ITF 60 mg iron was administered once a day to children weighing up to 40 kg; and twice a day to children with body weight equal or superior to 40 kg. Digestion ;50 2: Clin Ther ;10 4: Allergy and Immunology